Entry - *164865 - V-MYC AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG-LIKE 1; MYCLK1 - OMIM

 
 
* 164865

V-MYC AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG-LIKE 1; MYCLK1


Alternative titles; symbols

ONCOGENE MYC-LIKE-1
AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG LIKE-1


Cytogenetic location: 7p15     Genomic coordinates (GRCh38): 7:20,900,001-28,800,000


TEXT

▼ Cloning and Expression

Morton and Robertson (1991) used a 28-base oligonucleotide synthesized from the sequence in the second exon of MYC (190080) to isolate an 8.8-kb EcoRI fragment from a human genomic library. Sequence analysis showed a region with 85% identity to the 28-base oligonucleotide of MYC. An open reading frame of 207 nucleotides was found containing the region of homology.

▼ Mapping

By in situ hybridization, Morton and Robertson (1991) localized the MYCLK gene to chromosome 7. By chromosomal in situ hybridization, Robertson and Morton (1992) regionalized the gene to 7p15.


▼ REFERENCES

  1. Morton, C. C., Robertson, N. G. Isolation and characterization of a novel human myc-like (MYCLK) sequence.(Abstract) Cytogenet. Cell Genet. 58: 1924 only, 1991.

  2. Robertson, N. G., Morton, C. C. Mapping and characterization of a novel human myc-like (MYCLK1) sequence. Genomics 13: 449-451, 1992. [PubMed: 1612604, related citations] [Full Text]


Creation Date:
Victor A. McKusick : 8/20/1991
Edit History:
carol : 01/24/2014
mark : 6/9/1996
carol : 11/18/1994
carol : 5/29/1992
supermim : 3/16/1992
carol : 2/27/1992
carol : 2/22/1992
carol : 8/20/1991

* 164865

V-MYC AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG-LIKE 1; MYCLK1


Alternative titles; symbols

ONCOGENE MYC-LIKE-1
AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG LIKE-1


Cytogenetic location: 7p15     Genomic coordinates (GRCh38): 7:20,900,001-28,800,000


TEXT

Cloning and Expression

Morton and Robertson (1991) used a 28-base oligonucleotide synthesized from the sequence in the second exon of MYC (190080) to isolate an 8.8-kb EcoRI fragment from a human genomic library. Sequence analysis showed a region with 85% identity to the 28-base oligonucleotide of MYC. An open reading frame of 207 nucleotides was found containing the region of homology.

Mapping

By in situ hybridization, Morton and Robertson (1991) localized the MYCLK gene to chromosome 7. By chromosomal in situ hybridization, Robertson and Morton (1992) regionalized the gene to 7p15.


REFERENCES

  1. Morton, C. C., Robertson, N. G. Isolation and characterization of a novel human myc-like (MYCLK) sequence.(Abstract) Cytogenet. Cell Genet. 58: 1924 only, 1991.

  2. Robertson, N. G., Morton, C. C. Mapping and characterization of a novel human myc-like (MYCLK1) sequence. Genomics 13: 449-451, 1992. [PubMed: 1612604] [Full Text: https://doi.org/10.1016/0888-7543(92)90269-x]


Creation Date:
Victor A. McKusick : 8/20/1991

Edit History:
carol : 01/24/2014
mark : 6/9/1996
carol : 11/18/1994
carol : 5/29/1992
supermim : 3/16/1992
carol : 2/27/1992
carol : 2/22/1992
carol : 8/20/1991



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 4, 2024