HGNC Approved Gene Symbol: RPS25
Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,015,717-119,018,343 (from NCBI)
The mammalian ribosome is composed of 4 RNA species (see 180450) and approximately 80 different proteins, including RPS25.
Li et al. (1991) isolated a full-length cDNA clone encoding human ribosomal protein S25 (RPS25). The cDNA encoded a polypeptide of 125 amino acids with a deduced relative molecular weight of 13,750.
Through generation of sequence tagged sites for chromosome 11, Miwa et al. (1993) found that 1 cosmid marker contained part of the RPS25 gene. Imai et al. (1994) further validated its identity and, by direct fluorescence in situ hybridization, mapped it to 11q23.3. Kenmochi et al. (1998) confirmed the RPS25 mapping assignment reported by Imai et al. (1994).
Imai, T., Sudo, K., Miwa, T. Assignment of the human ribosomal protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis of the marker D11S456. Genomics 20: 142-143, 1994. [PubMed: 8020948] [Full Text: https://doi.org/10.1006/geno.1994.1145]
Kenmochi, N., Kawaguchi, T., Rozen, S., Davis, E., Goodman, N., Hudson, T. J., Tanaka, T., Page, D. C. A map of 75 human ribosomal protein genes. Genome Res. 8: 509-523, 1998. [PubMed: 9582194] [Full Text: https://doi.org/10.1101/gr.8.5.509]
Li, M., Latoud, C., Center, M. S. Cloning and sequencing a cDNA encoding human ribosomal protein S25. Gene 107: 329-333, 1991. [PubMed: 1748303] [Full Text: https://doi.org/10.1016/0378-1119(91)90335-9]
Miwa, T., Sudo, K., Nakamura, Y., Imai, T. Fifty sequenced-tagged sites on human chromosome 11. Genomics 17: 211-214, 1993. [PubMed: 8406452] [Full Text: https://doi.org/10.1006/geno.1993.1304]