HGNC Approved Gene Symbol: RPS13
Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:17,074,388-17,077,667 (from NCBI)
The mammalian ribosome is a macromolecular assembly of 4 RNA species (see 180450) and approximately 80 different proteins, including RPS13.
Chadeneau et al. (1993) cloned a cDNA encoding human RPS13. The deduced 151-amino acid RPS13 protein is identical to rat Rps13.
By sequence analysis, Caldwell et al. (2001) determined that the RPS13 gene contains 6 exons and spans approximately 2.7 kb.
By somatic cell hybrid and radiation hybrid mapping analyses, Kenmochi et al. (1998) mapped the human RPS13 gene to 11p. By sequence analysis, Caldwell et al. (2001) localized the gene to 11p15.1-p14.
Caldwell, G. M., Eddy, R. L., Day, C. D., Haley, L. H., Cooper, P. R., Sait, S. S. J., Hejtmancik, F., Smith, R. J. H., Morton, C. C., Higgins, M. J., Shows, T. B. Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1-p14. Cytogenet. Cell Genet. 92: 103-107, 2001. [PubMed: 11306805] [Full Text: https://doi.org/10.1159/000056877]
Chadeneau, C., LeMoullac, B., Denis, M. G. Cloning and analysis of the human S13 ribosomal protein cDNA. Nucleic Acids Res. 21: 2945 only, 1993. [PubMed: 8332508] [Full Text: https://doi.org/10.1093/nar/21.12.2945]
Kenmochi, N., Kawaguchi, T., Rozen, S., Davis, E., Goodman, N., Hudson, T. J., Tanaka, T., Page, D. C. A map of 75 human ribosomal protein genes. Genome Res. 8: 509-523, 1998. [PubMed: 9582194] [Full Text: https://doi.org/10.1101/gr.8.5.509]