Entry - *300028 - ZINC FINGER-, CCCH DOMAIN-, AND RNA-BINDING MOTIF-CONTAINING SERINE/ARGININE-RICH PROTEIN 2; ZRSR2 - OMIM

 
 
* 300028

ZINC FINGER-, CCCH DOMAIN-, AND RNA-BINDING MOTIF-CONTAINING SERINE/ARGININE-RICH PROTEIN 2; ZRSR2


Alternative titles; symbols

U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR, SMALL SUBUNIT 2; U2AF1RS2


HGNC Approved Gene Symbol: ZRSR2

Cytogenetic location: Xp22.2     Genomic coordinates (GRCh38): X:15,790,484-15,823,260 (from NCBI)


TEXT

▼ Cloning and Expression

Hatada et al. (1991) isolated the imprinted mouse gene U2af1rs1 by restriction landmark genomic scanning. This gene is related to the human ribonucleoprotein auxiliary factor (191317) required for RNA splicing.

Kitagawa et al. (1995) isolated 3 human homologs of mouse U2af1rs1. The predicted 482-amino acid protein is 92.1% identical to U2AF1RS1 (601079) and 75.1% identical to the mouse U2af1rs2 protein.


▼ Mapping

Kitagawa et al. (1995) mapped the ZRSR2 gene to chromosome Xp22.1 by fluorescence in situ hybridization.


▼ REFERENCES

  1. Hatada, I., Hayashizaki, Y., Hirotsune, S., Komatsubara, H., Mukai, T. A genomic scanning method for higher organisms using restriction sites as landmarks. Proc. Nat. Acad. Sci. 88: 9523-9527, 1991. [PubMed: 1946366, related citations] [Full Text]

  2. Kitagawa, K., Wang, X., Hatada, I., Yamaoka, T., Nojima, H., Inazawa, H., Abe, T., Mitsuya, K., Oshimura, M., Murata, A., Monden, M., Mukai, T. Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. Genomics 30: 257-263, 1995. [PubMed: 8586425, related citations] [Full Text]


Creation Date:
Alan F. Scott : 2/20/1996
Edit History:
alopez : 11/29/2010
mark : 6/25/1996
terry : 5/24/1996
terry : 5/22/1996
terry : 4/17/1996
terry : 3/27/1996
mark : 2/20/1996

* 300028

ZINC FINGER-, CCCH DOMAIN-, AND RNA-BINDING MOTIF-CONTAINING SERINE/ARGININE-RICH PROTEIN 2; ZRSR2


Alternative titles; symbols

U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR, SMALL SUBUNIT 2; U2AF1RS2


HGNC Approved Gene Symbol: ZRSR2

Cytogenetic location: Xp22.2     Genomic coordinates (GRCh38): X:15,790,484-15,823,260 (from NCBI)


TEXT

Cloning and Expression

Hatada et al. (1991) isolated the imprinted mouse gene U2af1rs1 by restriction landmark genomic scanning. This gene is related to the human ribonucleoprotein auxiliary factor (191317) required for RNA splicing.

Kitagawa et al. (1995) isolated 3 human homologs of mouse U2af1rs1. The predicted 482-amino acid protein is 92.1% identical to U2AF1RS1 (601079) and 75.1% identical to the mouse U2af1rs2 protein.


Mapping

Kitagawa et al. (1995) mapped the ZRSR2 gene to chromosome Xp22.1 by fluorescence in situ hybridization.


REFERENCES

  1. Hatada, I., Hayashizaki, Y., Hirotsune, S., Komatsubara, H., Mukai, T. A genomic scanning method for higher organisms using restriction sites as landmarks. Proc. Nat. Acad. Sci. 88: 9523-9527, 1991. [PubMed: 1946366] [Full Text: https://doi.org/10.1073/pnas.88.21.9523]

  2. Kitagawa, K., Wang, X., Hatada, I., Yamaoka, T., Nojima, H., Inazawa, H., Abe, T., Mitsuya, K., Oshimura, M., Murata, A., Monden, M., Mukai, T. Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. Genomics 30: 257-263, 1995. [PubMed: 8586425] [Full Text: https://doi.org/10.1006/geno.1995.9879]


Creation Date:
Alan F. Scott : 2/20/1996

Edit History:
alopez : 11/29/2010
mark : 6/25/1996
terry : 5/24/1996
terry : 5/22/1996
terry : 4/17/1996
terry : 3/27/1996
mark : 2/20/1996



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: April 18, 2024