Assessment of Tumor Angiogenesis
E. V. Stepanova, A. Yu. Baryshnikov, M. R. Lichinitser
Russian Cancer Research Center, Russian Academy of Medical Sciences,
Moscow, Russia A process of producing new capillaries from preexisting vessels induced by inflammation, immune reactions, and neoplasm is neoangiogenesis is analyzed. This process is required for the tumor growth and progression. The information about the major regulators of angiogenesis is generalized. The role of assessing neoangiogenesis for prediction of patient outcome, metastasis, and resistance to chemotherapy is discussed.
