Рис. G6PD seq

             Нуклеотидная и аминокислотная последовательности
            гена глюкозо-6 фосфат дегидрогеназы (G6PD)человека

                                               gcgcagacagcgtc

   atg gca gag cag gtg gcc ctg agc cgg acc cac gtg tgc ggg atc
   met ala glu gln val ala leu ser arg thr his val cys gly ile  15

   ctg cgg gaa gag ctt ttc cag ggc gat gcc ttc cat cag tcg gat
   leu arg glu glu leu phe gln gly asp ala phe his gln ser asp  30

                           +1
   aca cac ata ttc atc atc atg ggt gca tcg ggt gac ctg gcc aag
   thr his ile phe ile ile met gly ala ser gly asp leu ala lys  45

   aag aag atc tac ccc acc atc tgg tgg ctg ttc cgg gat ggc ctt
   lys lys ile tyr pro thr ile trp trp leu phe arg asp gly leu  60

   ctg ccc gaa aac acc ttc atc gtg ggc tat gcc cgt tcc cgc ctc
   leu pro glu asn thr phe ile val gly tyr ala arg ser arg leu  75

   aca gtg gct gac atc cgc aaa cag agt gag ccc ttc ttc aag gcc
   thr val ala asp ile arg lys gln ser glu pro phe phe lys ala  90

   acc cca gag gag aag ctc aag ctg gag gac ttc ttt gcc cgc aac
   thr pro glu glu lys leu lys leu glu asp phe phe ala arg asn 105

   tcc tat gtg gct ggc cag tac gat gat gca gcc tcc tac cag cgc
   ser tyr val ala gly gln tyr asp asp ala ala ser tyr gln arg 120

   ctc aac agc cac atg aat gcc ctc cac ctg ggg tca cag gcc aac
   leu asn ser his met asn ala leu his leu gly ser gln ala asn 135

   cgc ctc ttc tac ctg gcc ttg ccc ccg acc gtc tac gag gcc gtc
   arg leu phe tyr leu ala leu pro pro thr val tyr glu ala val 150

   acc aag aac att cac gag tcc tgc atg agc cag ata ggc tgg aac
   thr lys asn ile his glu ser cys met ser gln ile gly trp asn 165

   cgc atc atc gtg gag aag ccc ttc ggg agg gac ctg cag agc tct
   arg ile ile val glu lys pro phe gly arg asp leu gln ser ser 180

   gac cgg ctg tcc aac cac atc tcc tcc ctg ttc cgt gag gac cag
   asp arg leu ser asn his ile ser ser leu phe arg glu asp gln 195

   atc tac cgc atc gac cac tac ctg ggc aag gag atg gtg cag aac
   ile tyr arg ile asp his tyr leu gly lys glu met val gln asn 210

   ctc atg gtg ctg aga ttt gcc aac agg atc ttc ggc ccc atc tgg
   leu met val leu arg phe ala asn arg ile phe gly pro ile trp 225

   aac cgg gac aac atc gcc tgc gtt atc ctc acc ttc aag gag ccc
   asn arg asp asn ile ala cys val ile leu thr phe lys glu pro 240

   ttt ggc act gag ggt cgc ggg ggc tat ttc gat gaa ttt ggg atc
   phe gly thr glu gly arg gly gly tyr phe asp glu phe gly ile 255

   atc cgg gac gtg atg cag aac cac cta ctg cag atg ctg tgt ctg
   ile arg asp val met gln asn his leu leu gln met leu cys leu 270

   gtg gcc atg gag aag ccc gcc tcc acc aac tca gat gac gtc cgt
   val ala met glu lys pro ala ser thr asn ser asp asp val arg 285

   gat gag aag gtc aag gtg ttg aaa tgc atc tca gag gtg cag gcc
   asp glu lys val lys val leu lys cys ile ser glu val gln ala 300

   aac aat gtg gtc ctg ggc cag tac gtg ggg aac ccc gat gga gag
   asn asn val val leu gly gln tyr val gly asn pro asp gly glu 315

   ggc gag gcc acc aaa ggg tac ctg gac gac ccc acg gtg ccc cgc
   gly glu ala thr lys gly tyr leu asp asp pro thr val pro arg 330

   ggg tcc acc acc gcc act ttt gca gcc gtc gtc ctc tat gtg gag
   gly ser thr thr ala thr phe ala ala val val leu tyr val glu 345

   aat gag agg tgg gat ggg gtg ccc ttc atc ctg cgc tgc ggc aag
   asn glu arg trp asp gly val pro phe ile leu arg cys gly lys 360

   gcc ctg aac gag cgc aag gcc gag gtg agg ctg cag ttc cat gat
   ala leu asn glu arg lys ala glu val arg leu gln phe his asp 375

   gtg gcc ggc gac atc ttc cac cag cag tgc aag cgc aac gag ctg
   val ala gly asp ile phe his gln gln cys lys arg asn glu leu 390

   gtg atc cgc gtg cag ccc aac gag gcc gtg tac acc aag atg atg
   val ile arg val gln pro asn glu ala val tyr thr lys met met 405

   acc aag aag ccg ggc atg ttc ttc aac ccc gag gag tcg gag ctg
   thr lys lys pro gly met phe phe asn pro glu glu ser glu leu 420

   gac ctg acc tac ggc aac aga tac aag aac gtg aag ctc cct gac
   asp leu thr tyr gly asn arg tyr lys asn val lys leu pro asp 435

   gcc tac gag cgc ctc atc ctg gac gtc ttc tgc ggg agc cag atg
   ala tyr glu arg leu ile leu asp val phe cys gly ser gln met 450

   cac ttc gtg cgc agc gac gag ctc cgt gag gcc tgg cgt att ttc
   his phe val arg ser asp glu leu arg glu ala trp arg ile phe 465

   acc cca ctg ctg cac cag att gag ctg gag aag ccc aag ccc atc
   thr pro leu leu his gln ile glu leu glu lys pro lys pro ile 480

   ccc tat att tat ggc agc cga ggc ccc acg gag gca gac gag ctg
   pro tyr ile tyr gly ser arg gly pro thr glu ala asp glu leu 495

   atg aag aga gtg ggt ttc cag tat gag ggc acc tac aag tgg gtg
   met lys arg val gly phe gln tyr glu gly thr tyr lys trp val 510

   aac ccc cac aag ctc tga gccctgggcacccacctccacccccgccacggcca
   asn pro his lys leu ter

   ccctccttcccgccgcccgaccccgagtcgggaggactccgggaccattgacctcagct
   gcacattcctggccccgggctctggccacctggccgcccctcgctgctgctactacccg
   agcccagctacattcctcagctgccaagcactcgagaccatcttggcccctccagaccc
   tgcctgagcctaggagcttgagtcacctcctccactcactccagcccaacagaaggaag
   gaggagggcgcccattcgtctgtcccagagcttattggccactgggtctcgctccgagt
   ggggccagggtgggagggagggtcagggggaggaaaggggcgagcacccacgtgagaga
   atctgcctgtggccttgcccgccagcctcagtgccacttgacattccttgtcaccagca
   acatctcgagccccctggatgtcccctgtcccaccaactctgcactccatggccacccc
   gtgccacccgtaggcagcctctctgctataagaaaagcagacgcagcagctgggacccc
   tcccaacctcaatgccctgccattaaatccgcaaacagc

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