Gene: [00.0/ATIC] 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT; EC:2.1.2.3); IMP cyclohydrolase (IMPCHASE; 3.5.4.10); AICARFT/IMPCHASE;

FUN

AICARFT (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) and IMPCHase (IMP cyclohydrolase) catalyze the penultimate and final steps, respectively, of the de novo purine biosynthetic pathway (Rayl-1996)."

REF

CLO,SEQ,EXP,DOM "Rayl EA &: JBC, 271, 2225-2233, 1996

CLA

coding, basic

LOC

RS

MIM

MIM: 601731

EZN

ENZYME: 2.1.2.3

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