Gene: [00.0/EIF3S1] eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD);
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MOP |
[1] Eukaryotic translation initiation factor 3 is a large, multisubunit protein complex of approximately 600kD that play a central role in the pathway of initiation by promoting the binding of both methionyl-tRNAi and mRNA to the 40S ribosomal subunit. The protein complex consists of at least 10 subunits: eIF3-p35 (this gene product), eIF3-p36 (GEM:00.0/EIF3S2), eIF3-p40 (GEM:00.0/EIF3S3), eIF3-p44 (GEM:00.0/EIF3S4), eIF3-p47 (GEM:00.0/EIF3S5), eIF3-p48 (is encoded by INT6 gene, murine mammary tumor integration site 6; GEM:08q2/EIF3S6), eIF3-p66 (GEM:00.0/EIF3S7), eIF3-p110 (GEM:00.0/EIF3S8), eIF3-p116 (GEM:00.0/EIF3S9), and eIF3-p170 (GEM:10^/EIF3S10)." |
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REF |
CLO,SEQ "Block KL &: JBC, 273, N48, 31901-31908, 1998 |
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KEY |
trl |
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CLA |
coding, basic |
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LOC |
RS |
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MIM |
? |
