Gene: [00.0/EPX] eosinophil peroxidase; hereditary eosinophil peroxidase deficiency (Presentey anomaly; MIM:261500);

MOP

Eosinophil peroxidase is a heterotetramer of two light and two heavy chains which are located on the COOH and NH(2) terminus of the protein, respectively, both chains being coded by a single mRNA."

FAG

There are a few genes encoding proteins with the peroxidase activity: glutathione peroxidase (GEM:03p213/GPX1,...), lactoperoxidase (GEM:00.0/LPO), myeloperoxidase (GEM:17q2/MPO), and thyroid peroxidase (GEM:02p2/TPO)."

REF

PAT "Presentey BZ: Acta Haematol, 71, 334-340, 1984
PAT "Presentey BZ, Joshua H: Experientia, 38, 628-629, 1982
PAT "Presentey BZ: Acta Haematol, 44, 345-354, 1970
PAT "Presentey BZ, Szapiro L: Acta Haematol, 41, 359-362, 1969a
PAT "Presentey BZ: Am J Clin Path, 51, 458-462, 1969b
MUT "Romano M &: PNAS, 91, 12496-12500, 1994
CLO,SEQ,GEN "Sakamaki K &: JBC, 264, 16828-16836, 1989
CLO,SEQ,GEN "Ten RM &: J Exp Med, 169, 1757-1769, 1989
MUT "Yamaguchi Y &: JBC, 269, 19410-19419, 1994

SWI

 SWISSPROT: P11678

CLA

coding, basic

LOC

RS

MIM

 MIM: 131399

EZN

 ENZYME: 1.11.1.7