Gene: [00.0/EREG] epiregulin (EGF-related growth regulating peptide);
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FUN |
[1] Epiregulin functions as a tumor growth-inhibitory factor inducing
morphologic changes in HeLa cells (Toyoda-1995).
[2] In mice, epiregulin exhibited bifunctional regulatory properties: it inhibited the growth of several epithelial tumor cells and stimulated the growth of fibroblasts and various other types of cells (Toyoda-1995)." |
|
EXP |
The level of expression of epiregulin was extremely low almost in all tissues but clearly detectable in macrophages and placenta and was high in carcinoma cells (Toyoda-1997)." |
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REF |
FUN "Komurasaki T &: Oncogene, 15, N23, 2841-2848, 1997 COD,SEQ,EVO "Toyoda H &: Biochem J, 326, (Part 1), 69-75, 1997 FUN,EXP "Toyoda H &: JBC, 270, N13, 7495-7500, 1995 |
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KEY |
onc, trp |
|
CLA |
coding, basic |
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LOC |
RS |
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MIM |
MIM: 602061 |
