Gene: [00.0/HAS1] hyaluronan synthase 1;
|
FUN |
Hyaluronan is an unbranched glycosaminoglycan composed of repeating disaccharide units. It is a major constituent of the extracellular matrix and has been implicated in development, tumorigenesis, and several diseases. Hyaluronan is synthesized at the inner face of the plasma membrane and is subsequently extruded to the outside of the cell." |
|
FAG |
The following genes coding for hyaluronan synthase have been found: GEM:00.0/HAS2; GEM:16q221/HAS3." |
|
REF |
CLO,SEQ,EXP "Itano N, Kimata K: BBRC, 222, 816-820, 1996a CLO,SEQ,EXP "Itano N, Kimata K: JBC, 271, 9875-9878, 1996b CLO,SEQ,EXP "Shyjan AM &: JBC, 271, 23395-23399, 1996 |
|
KEY |
onc, exce |
|
CLA |
coding, basic |
|
LOC |
RS |
|
MIM |
MIM: 601463 |
|
EZN |
? |
