Gene: [00.0/MMP18] matrix metalloproteinase 18;
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COM |
Cossins-1996 identified a partial cDNA clone that encoded the 3-prime end of a putative MMP which they called MMP-18. The 5-prime end was amplified by PCR and the full-length cDNA was cloned and sequenced. MMP18 contains an open reading frame of 508 amino acids with a predicted molecular weight of 57,238 and has all the characteristic features of the MMP family (FAM:MMP/00.0). MMP18 contains a putative signal sequence, followed by a prodomain with a conserved 'cysteine switch' region." |
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REF |
COD,EXP,EVO "Cossins J &: BBRC, 228, 494-498, 1996 |
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KEY |
exce, pep |
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CLA |
coding, basic |
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LOC |
RS |
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MIM |
MIM: 601807 |
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EZN |
ENZYME: 3.4.24.? |
