Gene: [00.0/PAK1] p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); serine/threonine kinase PAK-alpha;
FUN | PAK1 is a GTPase effector controlling a downstream MAP kinase pathway in mammalian cells, as Ste20 does in yeast. PAK and Ste20 kinases play key parts in linking extracellular signals from membrane components, such as receptor-associated G proteins and Rho-related GTPases, to nuclear responses, such as transcriptional activation (Brown-1996)." |
REL | GEM:00.0/PAK3. |
REF | CLO,SEQ,FUN
"Brown JL &: Curr Biol, 6, N5, 598-605, 1996 |
SWI | SWISSPROT: Q13153 |
CLA | coding, basic |
LOC | RS |
MIM | MIM: 602590 |
EZN | ENZYME: 2.7.1.? |
