Gene: [00.0/RAB9] oncogene RAS-family, member rab9;
SUM | In studies using antisense RNA, Davies-1997 found that downregulation of RAB9 gene expression in HeLa cells induces severe cell vacuolation that resembles the phenotype seen in fibroblasts from patients with Chediak-Higashi syndrome (GEM:01q42/CHS1). The authors identified a RAB9 pseudogene whose nucleotide sequence is 90% identical to that of RAB9. They mapped the pseudogene to Chr 5 (GEM:05^/RAB9P) by PCR analysis of somatic cell hybrid DNAs." |
PSG | GEM:05^/RAB9P. |
REF | CLO,FAG
"Davies JP &: Genomics, 41, N1, 131-134, 1997 |
SWI | SWISSPROT: P51151 |
KEY | onc |
CLA | coding, basic |
LOC | RS |
MIM | MIM: 602299 |
