Gene: [00.0/REST] neuron restrictive silencer factor; [NRSF ]

FUN

Schoenherr-1995 cloned a transcription factor they termed neuron-restrictive silencer factor (NRSF) that represses transcription of SCG10 (see GEM:00.0/SCG10) by binding to a 24-bp regulatory element, called the neuron-restrictive silencer element (NRSE), located in the distal 5-prime regulatory region of the gene."

REF

CLO,SEQ "Chong JA &: Cell, 80, 949-957, 1995
CLO,SEQ "Schoenherr CJ, Anderson DJ: Science, 267, 1360-1363, 1995

KEY

trc

CLA

coding, basic

LOC

RS

MIM

MIM: 600571

SYN

NRSF