Gene: [00.0/SCYA23] small inducible cytokine subfamily A (Cys-Cys), member 23; myeloid progenitor inhibitory factor 1 (CK-beta-8); [MPIF1 Ckb-8 ]
|
FUN |
SCYA23 has chemotactic activity on resting T lymphocytes and monocytes, and lower activity on neutrophils. SCYA23 also inhibits, in vitro, hematopoietic progenitor cells that give rise to granulocyte and monocyte lineages (Patel-1997)." |
|
MOP |
SCYA23 encodes a predicted 120-amino acid protein that contains a 21-amino acid N-terminal signal peptide. The SCYA23 protein, which migrates as a 11- to 12-kD band on SDS-PAGE, is 51% identical to that of MIP-1-alpha (GEM:17q112/SCYA3)." |
|
FAG |
On myeloid progenitor inhibitory factor 2 see in GEM:00.0/SCYA24. |
|
REF |
COD,SEQ,FAG "Patel VP &: J Exp Med, 185, N7, 1163-1172, 1997 |
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KEY |
imm, cyk |
|
CLA |
coding, basic |
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LOC |
RS |
|
MIM |
MIM: 602494 |
|
SYN |
MPIF1 Ckb-8 |
