Gene: [01p131/HSD3B1] hydroxy-delta-5-steroid (3 beta-) dehydrogenase 1 (EC:1.1.1.145); steroid delta-isomerase 1 (EC:5.3.3.1);

FUN

[1] EC:1.1.1.145: Systematic name: 3-beta-hydroxy-delta-5-steroid:NAD(+) 3-oxidoreductase. Catalyzed reaction: 3-beta-hydroxy-delta-5-steroid + NAD(+) = 3-oxo-delta-5-steroid + NADH.
[2] EC:5.3.3.1: Catalyzed reaction: 3-oxo-delta-5-steroid = 3-oxo-delta-4-steroid."

REL

GEM:01p131/HSD3B2; GEM:00.0/HSD3B3.

REF

LOC,CYG,MOL,PRO "Berube &: CCG, 51, (HGM10), 962, 1989

SWI

SWISSPROT: P14060

KEY

ster, horm, sex, mem

CLA

coding, basic

LOC

01 p13.1

MIM

MIM: 109715

EZN

ENZYME: 1.1.1.145

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