Gene: [01p13/NGFB] nerve growth factor, beta polypeptide;

LIN

Loci: GEM:01p13/TSHB.
[1] NGFB is tightly linked with TSHB [0cM][<=320kb]. com="/TD">

EXP

The expression of NGFB is stimulated, and that of TSHB is suppressed, by thyroid hormones (TH). Similar TH-dependent differential expression is characteristic for the genes of alpha- and beta-chains of myosin. Similar regulatory binding sites might exist in intervening spacers that account for antithetic regulation of transcription in the TH-dependent gene clusters."

PRO

Probe N8C6 identifies BglII, TaqI, and HincII RFLPs.

REF

LIN,MAP,POL "Anderson &: CCG, 51, (HGM10), 951, 1989
POL "Breakefield XO &: PNAS, 81, N13, 4213-4216, 1984
LOC,MAP,EXP "Dracopoli NC &: Genomics, 3, N2, 161-167, 1988
FUN,EXP,RAT "Lindsay, Harmar: Nature, 337, (26 Jan), 362-364, 1989
LOC,CYG "Munke &: CCG, 40, (HGM8), 705-706, 1985
SEQ,EAG "Ullrich A &: Cold Spring Harbor Symp, 48, (Part 1), 435-442, 1983a
PRO,SEQ,CAG "Ullrich A &: Nature, 303, (30 Jun), 821-825, 1983b
LOC "Zabel BU &: PNAS, 82, 469-473, 1985

SWI

SWISSPROT: P01138

KEY

neu, cyk

CLA

coding, basic

LOC

01 p13

MIM

MIM: 162030

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