Gene: [01p32/PTPRF] protein tyrosine phosphatase, receptor type, f polypeptide; leukocyte antigen related tyrosine phosphatase;
MOP |
The gene product is a membrane-associated protein with putative receptor-like function. Its cytoplasmic part is homologous to the 1B tyrosine phosphatase (GEM:20q13/PTPN1) while the extracellular part is homologous to the neural cell adhesion protein (GEM:11q2/NCAM1)." |
FUN |
[1] Systematic name: protein-tyrosine-phosphate phosphohydrolase.
[2] Reaction catalyzed: protein tyrosine phosphate + H(2)O = protein tyrosine + orthophosphate." |
REF |
PRO,LOC "Cockburn DJ &: CCG, 58 (HGM11), N1-4, 1851, 1991 PRO,LOC "Disteche CM &: CCG, 51 (HGM10), N1-4, 990, 1989 IDN,FUN,PEP "Foulkes JG &: FEBS Lett, 130, N2, 197-200, 1981 IDN,FUN,PEP "Gallis B &: PNAS, 78, N11, 6689-6693, 1981 LOC "Harder KW &: Genomics, 27, N3, 552-553, 1995 LOC "Jirik FR &: CCG, 61, N4, 266-268, 1992 CLO,SEQ "Kaplan R &: PNAS, 87, N18, 7000-7004, 1990 CLO,SEQ,GEN,MOP "O'Grady P &: JBC, 269, N40, 25193-25199, 1994 |
KEY |
mem, pep, recp |
CLA |
coding, basic |
LOC |
01 p32 |
MIM |
MIM: 179590 |
EZN |
ENZYME: 3.1.3.48 |