Gene: [01p32/PTPRF] protein tyrosine phosphatase, receptor type, f polypeptide; leukocyte antigen related tyrosine phosphatase;

MOP

The gene product is a membrane-associated protein with putative receptor-like function. Its cytoplasmic part is homologous to the 1B tyrosine phosphatase (GEM:20q13/PTPN1) while the extracellular part is homologous to the neural cell adhesion protein (GEM:11q2/NCAM1)."

FUN

[1] Systematic name: protein-tyrosine-phosphate phosphohydrolase.
[2] Reaction catalyzed: protein tyrosine phosphate + H(2)O = protein tyrosine + orthophosphate."

REF

PRO,LOC "Cockburn DJ &: CCG, 58 (HGM11), N1-4, 1851, 1991
PRO,LOC "Disteche CM &: CCG, 51 (HGM10), N1-4, 990, 1989
IDN,FUN,PEP "Foulkes JG &: FEBS Lett, 130, N2, 197-200, 1981
IDN,FUN,PEP "Gallis B &: PNAS, 78, N11, 6689-6693, 1981
LOC "Harder KW &: Genomics, 27, N3, 552-553, 1995
LOC "Jirik FR &: CCG, 61, N4, 266-268, 1992
CLO,SEQ "Kaplan R &: PNAS, 87, N18, 7000-7004, 1990
CLO,SEQ,GEN,MOP "O'Grady P &: JBC, 269, N40, 25193-25199, 1994

KEY

mem, pep, recp

CLA

coding, basic

LOC

01 p32

MIM

MIM: 179590

EZN

ENZYME: 3.1.3.48

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