Gene: [01p361/HSPG2] heparan sulfate proteoglycan 2 (perlecan, 400kD); [PlC ]
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COM |
[1] Three data sets relating to a regional location of HSPG2 are
published:
(1) Kallunki-1990: Chr 1p36.1-35, with a maximal hybridization signal at the band 1p35; (2) Wintle-1990: Chr 1p36.1, without any secondary sites of hybridisation (both using radioactive chromosomal in situ hybridization); and (3) Dodge-1991: Chr 1p36-p34, using Southern blot analysis of DNA from human-rodent somatic cell hybrids. Genome Data Base indicates a broader location (GDB:G00-126-372:LOC='01 p36.1-35') established by Kallunki whereas HUGEN uses the one established by Wintle. [2] HSPG1 related to HSPG2 and encoding a 48/90kD proteoglycan - fibroglycan - was mapped to Chr 8q2 (GEM:08q2/SDC2)." |
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REF |
CLO,SEQ,COD,LOC,MOL "Dodge GR &: Genomics, 10, N3 (Jul), 673-680, 1991 IDN,FUN,MOP,STR,HET "Gallagher JT &: Biochem J, 236, 313-325, 1986 IDN,FUN,MOP,STR,HET "Hassel JR &: Annu Rev Biochem, 55, 539-567, 1986 IDN,FUN,MOP,STR,HET "Heremans A &: J Cell Biol, 109, 3199-3211, 1989 IDN,FUN,MOP,STR,HET "Iozzo RV &: JBC, 265, 19980-19989, 1990 IDN,FUN,MOP,STR,HET "Iozzo RV, Hassel JR: Arch Biochem Biophys, 269, 239-249, 1989 IDN,FUN,MOP,STR,HET "Iozzo RV: J Cell Biol, 99, 403-417, 1984 CLO,SEQ,COD,LOC,POL,MOL "Kallunki P &: Genomics, 11, N2 (Oct), 389-396, 1991 IDN,FUN,MOP,STR,HET "Klein DJ &: J Cell Biol, 106, 963-970, 1988 IDN,FUN,MOP,STR,HET "Ledbetter SR &: JBC, 260, 8106-8113, 1985 IDN,FUN,MOP,STR,HET "Lories V &: JBC, 264, N12, 7009-7016, 1989 IDN,FUN,MOP,STR,HET "Lories V &: JBC, 262, 854-859, 1987 IDN,FUN,MOP,STR,HET "Noonan DM &: JBC, 263, 16379-16387, 1988 PAT,MEB "Vernier RL &: New Engl J Med, 309, 1001-1009, 1983 LOC,CYG,MOL "Wintle RF &: CCG, 54, 60-61, 1990 |
|
KEY |
mem |
|
CLA |
coding, basic |
|
LOC |
01 p36.1 |
|
MIM |
MIM: 142461 |
|
SYN |
PlC |
