Gene: [01p3/HTR1D] 5-hydroxytryptamine (serotonin) receptor 1D; [HTRL RDC4 ]
|
COM |
[1] A few other HTR1 functional genes and one non-functional copy of
HTR1D are identified; most of them have been mapped to particular
chromosomes. In addition, serotonin transporter (GEM:17q1/SLC6A4)
has been also mapped.
[2] The molecular product is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter (a hormone and a mitogen). The activity of this receptor is mediated by G proteins inhibiting adenylate cyclase." |
|
REF |
CLO,COD,SEQ,STR,FUN "Hamblin MW, Metcalf MA: Mol Pharmacol, 40, 143-148,
1991 LOC,MOL "Libert F &: Genomics, 11, N1 (Sep), 225-227, 1991 CLO,COD,SEQ,LOC,MOL "Weinshank RL &: PNAS, 89, 3630-3634, 1992 |
|
KEY |
neu, recp, sign |
|
CLA |
coding, basic |
|
LOC |
01 p36.3-34.3 |
|
MIM |
MIM: 182133 |
|
SYN |
HTRL RDC4 |
