Gene: [01q21/DAP3] death-associated protein 3;

COM

Kissil and Kimchi (Kissil-1997) mapped the DAP3 gene to Chr 1q21 by fluorescence in situ hybridization. Verification of the assignment was achieved by identifying the gene in a YAC contig encompassing Chr 1q21.1-21.3."

FUN

Being a positive mediator of interferon-gamma-induced cell death, DAP3 may be a tumor suppressor gene subjected to loss or inactivation in tumors."

REF

LOC "Kissil JL, Kimchi A: CCG, 77, N3-4, 252-252, 1997
COD,SEQ,EXP "Kissil JL &: JBC, 270, 27932-27936, 1995

KEY

ont, onc

CLA

coding, basic

LOC

01 q21

MIM

MIM: 602074

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