Gene: [01q2/FMO4] flavin containing monooxygenase 4 (adult liver);

FUN

[1] Systematic name: N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide forming).
[2] The reaction catalyzed: N,N-dimethylaniline + NADPH + O(2) = = N,N-dimethylaniline N-oxide + NADP(+) + H(2)O.
[3] Cofactor: FAD."

REL

See GEM:01q2/FMO1.

REF

COD,SEQ,LOC,EVO "Dolphin CT &: Biochem J, 287, 261-267, 1992
COD,SEQ "Lomri N &: PNAS, 89, 1685-1689, 1992
REV,PAT,TER "Mitchell SC: Perspect Biol Med, 39, 514-526, 1996
PRO,LOC,FAG "Shephard EA &: Genomics, 16, 85-89, 1993
LOC,FAG "Shephard EA &: CCG, 58, 1863-1863, 1991

KEY

xen

CLA

coding, basic

LOC

01 q23-25

MIM

MIM: 136131

EZN

ENZYME: 1.14.13.8

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