Gene: [01q2/POU2F1] POU domain, class 2, transcription factor 1; octamer-binding transcription factor 1 (B-cell specific); [OTF1 OCT1 ]
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FUN |
Products of the OTF genes are thought to bind octanucleotide ATTTGCAT, which is contained in promoters of immunoglobulin genes and plays a critical role in the tissue-specific restriction of their expression, predominantly by lymphoid cells." |
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REF |
IDN,FUN,EXP "Fletcher C &: Cell, 51, N5, 773-781, 1987 PRO,LOC "Hsieh CL &: Genomics, 6, 666-672, 1990 PRO,LOC "Hsieh CL &: CCG, 51, (HGM10), 1016, 1989 MAF,MOU "Oakey RJ &: Hum Mol Genet, 1, 613-620, 1992 LOC,MAF "Sturm RA &: CCG, 68, 231-232, 1995 EXP "Sturm RA &: Genomics, 16, 333-341, 1993 LOC,SEQ "Sturm RA &: Genes Dev, 2, 1582-1599, 1988 |
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KEY |
trc, imm, img |
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CLA |
coding, basic |
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LOC |
01 q22-23 |
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MIM |
MIM: 164175 |
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SYN |
OTF1 OCT1 |
