Gene: [01q2/SELL] selectin L; lymphocyte adhesion molecule 1 (lymph node homing receptor); [LYAM1 LAM1 ]
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FAG |
Three other cell adhesion factor genes are located in the long arm of Chr 1. These are the endothelial (GEM:01q2/SELE), granulocyte (GEM:01q2/SELP), and CD34 antigen (GEM:01q/CD34) cell adhesion factors. The genes SELE, SELL, and SELP belong to a selectin multigene family, which peptide products have a common feature in their structure: functionally similar domains are located in the same order (from N- to C-end: lectin-like - EGF-like - two src-like - transmembrane)." |
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REF |
CLO,SEQ,LOC "Bevilacqua MP &: Science, 243, 1160-1165, 1989 LOC,PRO "Disteche &: CCG, 51, (HGM10), 950, 1989 CLO,SEQ,LOC "Disteche CM &: CCG, 51, 990, 1989 CLO,SEQ,LOC "Ryan US &: Curr Opin Immunol, 4, 33-37, 1992 CLO,SEQ,LOC,EAG,FAG "Tedder TF &: J Exp Med, 170, (Jul), 123-133, 1989 CLO,SEQ,LOC "Watson ML &: J Exp Med, 172, 263-272, 1990 POL "Wenzel K &: Hum Mol Genet, 3, 1935-1937, 1994 |
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KEY |
imm, mem, recp |
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CLA |
coding, basic |
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LOC |
01 q23-25 |
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MIM |
MIM: 153240 |
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SYN |
LYAM1 LAM1 |
