Gene: [01q321/ADORA1] adenosine A1 receptor; [RDC7 ]

COM

Previously ADORA1 has been mapped to 22q11.2-q13.1 (in situ hybridization; Libert-1991). Later Libert et al. had verified the sequences of the clones used as probes in their localization study and concluded that their probe was not ADORA1. Townsend-Nicholson-1995 located ADORA1 to 1q32.1 based upon both the mapping of the cDNA and the mapping of a cosmid containing the A1 receptor subtype gene."

FUN

The adenosine receptors regulate a diverse set of physiologic functions including cardiac rate and contractility, smooth muscle tone, sedation, release of neurotransmitters, platelet function, lipolysis, renal function, and white blood cell function (reviewed in Stiles-1992)."

REF

HIS,COM "Libert F &: Genomics, 11, 225-227, 1991
REV,FUN,MOP,FAG "Stiles &: JBC, 267, 6451-6454, 1992
PRO,LOC "Townsend-Nicholson A &: Genomics, 26, 423-425, 1995
COD,SEQ,FUN,EXP "Townsend-Nicholson A &: Mol Brain Res, 16, 365-370, 1992

SWI

SWISSPROT: P30542

KEY

nucm, recp, mem, neu

CLA

coding, basic

LOC

01 q32.1

MIM

MIM: 102775

SYN

RDC7

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