Gene: [01q32/C4BPA] complement component 4-binding protein, alpha (70kD); [C4BP ]

COM

Pardo-Manuel-1990 mapped the C4BP alpha and C4BP beta (GEM:01q32/C4BPB) genes to Chr 1q32 and found them to be closely linked, about 3.5-5 kb apart, in head-to-tail position."

FAG

C4BPA belongs to the group of structurally and functionally related serum glycoproteins that regulate the complement activation; see FAM:RCA/01q32."

PRO

Probe A500 have been obtained from pDP2 clone (a derivative of the clone pAT 153/PVU 11/8). It represents a 1.5-kb BamHI/ClaI cDNA fragment."

REL

GEM:01q32/C4BPAL1; GEM:01q32/C4BPAL2; GEM:01q32/C4BPB.

REF

CLO,COD,SEQ "Chung LP &: Biochem J, 230, 133-141, 1985a
PEP,SEQ "Chung LP &: Mol Immunol, 22, 427-435, 1985b
LOC,PRO "Hing &: Ann Hum Genet, 52, 117-122, 1988
COM "Klickstein LB &: J Exp Med, 165, 1095-1112, 1987
CLO,LOC "Pardo-Manuel F &: PNAS, 87, 4529-4532, 1990
LOC,LIN,MAF "Rey-Campos J &: J Exp Med, 167, 664-669, 1988
LOC,LIN,MAF "Rey-Campos J &: J Exp Med, 166, 246-252, 1987
FAG,MAP "Rodriguez de Cordoba S, Rubinstein: Immunogenetics, 25, 267-268, 1986a
FAG,MAP "Rodriguez de Cordoba S, Rubinstein: J Exp Med, 164, N4, 1274-1283, 1986b
LOC,LIN "Rodriguez de Cordoba S &: J Exp Med, 161, 1189-1195, 1985
LOC,LIN "Rodriguez de Cordoba S &: PNAS, 81, 7890-7892, 1984
LOC,CYG "Weis &: Immunology, 138, 312-315, 1987
GEN,STR,SEQ,LOC "Wong WW &: J Exp Med, 169, 847-863, 1989

SWI

 SWISSPROT: P04003

KEY

imm, comp, hem, serp

CLA

coding, basic

LOC

01 q32

MIM

 MIM: 120830

SYN

C4BP

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