Gene: [02p1/CDK7] cyclin-dependent kinase 7 (42kD; homolog of Xenopus MO15 cdk-activating kinase); serine/threonine kinase 1;
FAG | [1] The
mammalian CDK-activating kinase (CAK) is composed of 2 major polypeptides,
cyclin H (GEM:05q1/CCNH), and CDK7 kinase
(Fisher-1994). Shiekhattar-1995 gave evidence that CAK complex is a
component of transcription factor TFIIH (see GEM:11p1/GTF2H1). [2] On other serine/threonine kinases see GEM:03p211/STK2, GEM:00.0/STK3, GEM:00.0/STK4, and GEM:20q13/STK6." |
REF | CLO,SEQ "Darbon J-M &:
Oncogene, 9, 3127-3138, 1994 CLO,SEQ "Fisher RP, Morgan DO: Cell, 78, 713-724, 1994 CLO,SEQ,LOC "Levedakou EN &: Oncogene, 9, 1977-1988, 1994 FUN "Shiekhattar R &: Nature, 374, 283-287, 1995 CLO,SEQ "Tassan J-P &: J Cell Biol, 127, 467-478, 1994 CLO,SEQ "Wu L &: Oncogene, 9, 2089-2096, 1994 |
SWI | SWISSPROT: P50613 |
KEY | ont, pep |
CLA | coding, basic |
LOC | 02 p15-c |
MIM | MIM: 601955 |
EZN | ENZYME: 2.7.1.? |
