Gene: [02q1/GABRI] diazepam binding inhibitor; acyl-CoA binding protein; anxiety, pathologic (liability?); [DBI ACBP ]
COM | The original report (De Bernardi-1988), as well as the GDB indicates a less definite gene localization (q12-21), although data exist that suggest more narrow localization, q13-14." |
FAG | It is likely that the genome contains several other DBI-like sequences (coding ones or pseudogenes) in the genome. According to the data on in situ hybridization of cDNA probe on chromosomes, DBIL genes are probably located in Chrs 5, 6, and 19 (the authors also mention Chrs 11 and 14); see GEM:05^/GABRIL1, GEM:06^/GABRIL2, GEM:11^/GABRIL3, and GEM:14^/GABRIL4)." |
REF | FUN,PEP "Anholt &:
JBC, 261, 576-583, 1986 LOC,FAG "DeBernardi MA &: PNAS, 85, N17, 6561-6565, 1988 FUN,PEP "Ferrero &: PNAS, 83, N3, 827-831, 1986 FUN,PEP "Gray PW: Neuropharmacology, 26, (N7B), 863-865, 1987 CLO,SEQ,EXP,EVO "Gray PW &: PNAS, 83, N19, 7547-7551, 1986 FUN,PEP "Guidotti &: PNAS, 80, 3531-3535, 1983 FUN,PEP "Marquardt H &: JBC, 261, 9727-9731, 1986 CLO,SEQ,EXP,EVO "Mocchetti I &: PNAS, 83, N19, 7221-7225, 1986 CLO,SEQ,EXP,EVO "Webb NR &: DNA, 6, 71-79, 1987 |
SWI | SWISSPROT: P07108 |
KEY | neu, recp, sign |
CLA | coding, basic |
LOC | 02 q13-14 |
MIM | MIM: 125950 |
SYN | DBI ACBP |