Gene: [02q1/GABRI] diazepam binding inhibitor; acyl-CoA binding protein; anxiety, pathologic (liability?); [DBI ACBP ]

COM

The original report (De Bernardi-1988), as well as the GDB indicates a less definite gene localization (q12-21), although data exist that suggest more narrow localization, q13-14."

FAG

It is likely that the genome contains several other DBI-like sequences (coding ones or pseudogenes) in the genome. According to the data on in situ hybridization of cDNA probe on chromosomes, DBIL genes are probably located in Chrs 5, 6, and 19 (the authors also mention Chrs 11 and 14); see GEM:05^/GABRIL1, GEM:06^/GABRIL2, GEM:11^/GABRIL3, and GEM:14^/GABRIL4)."

REF

FUN,PEP "Anholt &: JBC, 261, 576-583, 1986
LOC,FAG "DeBernardi MA &: PNAS, 85, N17, 6561-6565, 1988
FUN,PEP "Ferrero &: PNAS, 83, N3, 827-831, 1986
FUN,PEP "Gray PW: Neuropharmacology, 26, (N7B), 863-865, 1987
CLO,SEQ,EXP,EVO "Gray PW &: PNAS, 83, N19, 7547-7551, 1986
FUN,PEP "Guidotti &: PNAS, 80, 3531-3535, 1983
FUN,PEP "Marquardt H &: JBC, 261, 9727-9731, 1986
CLO,SEQ,EXP,EVO "Mocchetti I &: PNAS, 83, N19, 7221-7225, 1986
CLO,SEQ,EXP,EVO "Webb NR &: DNA, 6, 71-79, 1987

SWI

SWISSPROT: P07108

KEY

neu, recp, sign

CLA

coding, basic

LOC

02 q13-14

MIM

MIM: 125950

SYN

DBI ACBP

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