Gene: [03q13/MOX2] antigen MOX2 (monoclonal antibody MRC-OX2); MRC OX-2 membrane glycoprotein; [MOX1 ]
FUN | Specific function is not known yet. |
IDN | The antigen was identified using murine monoclonal antibodies against the membrane proteins of rat T lymphocytes." |
MOP | Two isoforms are known, the thymocytic one with MM 47 kD and the cerebral one with MM 41 kD, which differ in the proportion of glycosilated amino acid residues (33 and 24%, respectively). The polypeptide translation product contains 248 amino acids, 202 C-terminal ones forming the extracellular part consisting of two domains. These domains have a structure similar to that of immunoglobulin peptides." |
PRO | Gene-specific DNA probe HX2/HIII (a 3.8 kb fragment) has been cloned at HindIII site in the plasmid pUC18." |
POL | EcoRI A-RFLP (Douglas-1988; Probe [1]): allele A1= 6.8 kb/(popul freq= 0.62); allele A2= 3.8/(0.38)" |
REF | PRO,POL "Douglas J &:
NAR, 16, 9067, 1988 FUN,CLO,SEQ,MOP,LOC "McCaughan GW &: Immunogenetics, 25, 133-135, 1987 |
SWI | SWISSPROT: P41217 |
KEY | mem, img |
CLA | coding, basic |
LOC | 03 q13 |
MIM | MIM: 155970 |
SYN | MOX1 |