Gene: [03q26/PI12] protease inhibitor 12 (neuroserpin);

COM

The PI12 gene was mapped to chromosome 3q26 by FISH (Schrimpf-1997).

TIS

Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons (Stoeckli-1989). It is expressed in the late stages of neurogenesis during the process of synapse formation. The PI12 gene is expressed as a 1.8-kb transcript, predominantly in the brain (Schrimpf-1997)."

REF

COD,SEQ,LOC "Schrimpf SP &: Genomics, 40, 55-62, 1997
MEB,EXP "Stoeckli ET &: Eur J Biochem, 180, 249-258, 1989

KEY

serp, neu

CLA

coding, basic

LOC

03 q26

MIM

MIM: 602445

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