Gene: [03q26/PI12] protease inhibitor 12 (neuroserpin);
COM |
The PI12 gene was mapped to chromosome 3q26 by FISH (Schrimpf-1997). |
TIS |
Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons (Stoeckli-1989). It is expressed in the late stages of neurogenesis during the process of synapse formation. The PI12 gene is expressed as a 1.8-kb transcript, predominantly in the brain (Schrimpf-1997)." |
REF |
COD,SEQ,LOC "Schrimpf SP &: Genomics, 40, 55-62, 1997 MEB,EXP "Stoeckli ET &: Eur J Biochem, 180, 249-258, 1989 |
KEY |
serp, neu |
CLA |
coding, basic |
LOC |
03 q26 |
MIM |
MIM: 602445 |