Gene: [04p163/ADD1] adducin 1 (alpha); [ADDA ]
FUN | Adducin is thought to play a role in assembling of the spectrin-actin lattice, which underlies the plasma membrane. Erythrocytic adducin promotes the binding of actin with spectrin and the Ca(2+)/calmodulin-dependent binding of additional spectrin molecules with the actin-spectrin complex." |
MOP | Adducin is a heterodimeric calmodulin-binding protein. |
REL | GEM:02p1/ADD2; GEM:00.0/ADD3; GEM:10q24/ADDL. |
REF | COD,EXP,REL "Goold RD
&: Hum Mol Genet, 2, 1271-1288, 1993 COD,SEQ,EXP,PEP,MOP,FAG "Joshi RL &: J Cell Biol, 115, 665-675, 1991 LOC,SEQ,EXP "Taylor SA &: Nature Genet, 2, N3, 223-227, 1992 |
SWI | SWISSPROT: P35611 |
KEY | hem, cysk |
CLA | coding, basic |
LOC | 04 p16.3 |
MIM | MIM: 102680 |
SYN | ADDA |