Gene: [04p163/ADD1] adducin 1 (alpha); [ADDA ]

FUN

Adducin is thought to play a role in assembling of the spectrin-actin lattice, which underlies the plasma membrane. Erythrocytic adducin promotes the binding of actin with spectrin and the Ca(2+)/calmodulin-dependent binding of additional spectrin molecules with the actin-spectrin complex."

MOP

Adducin is a heterodimeric calmodulin-binding protein.

REL

GEM:02p1/ADD2; GEM:00.0/ADD3; GEM:10q24/ADDL.

REF

COD,EXP,REL "Goold RD &: Hum Mol Genet, 2, 1271-1288, 1993
COD,SEQ,EXP,PEP,MOP,FAG "Joshi RL &: J Cell Biol, 115, 665-675, 1991
LOC,SEQ,EXP "Taylor SA &: Nature Genet, 2, N3, 223-227, 1992

SWI

SWISSPROT: P35611

KEY

hem, cysk

CLA

coding, basic

LOC

04 p16.3

MIM

MIM: 102680

SYN

ADDA

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