Gene: [05q11/IL6ST] interleukin 6 signal transducer, gp130 (oncostatin M receptor; antigen CDW130);
COM | Rodriguez-1995 assigned the active IL6ST gene to Chr 5q11 and the nontranscribed IL6ST pseudogene (GEM:17p11/IL6STP) to Chr 17p11." |
FUN | gp130 is involved in signal transduction of interleukin 6 (GEM:07p21/IL6), interleukin 11 (GEM:19q13/IL11), leukemia inhibitory factor (GEM:22q12/LIF), oncostatin M (GEM:22q12/OSM), and ciliary neurotrophic factor (GEM:11q12/CNTF)." |
PSG | GEM:17p11/IL6STP. |
REF | SEQ "Hibi M &: Cell,
63, 1149-1157, 1990 CLO "Kidd VJ &: Somat Cell Mol Genet, 18, 477-483, 1992 CLO,LOC "Rodriguez C &: CCG, 70, 64-67, 1995 |
SWI | SWISSPROT: P40189 |
KEY | imm, recp, mem, sign |
CLA | coding, basic |
LOC | 05 q11 |
MIM | MIM: 600694 |
