Gene: [05q31/PITX1] pituitary homeo box 1; paired-like homeodomain transcription factor 1; backfoot (mouse) homolog; [PTX1 BFT ]

COM

Fluorescence in situ hybridization placed the human gene on Chr 5q31 (Crawford-1997)."

FAG

The PTX1, GEM:04q25/PITX2, and GEM:10q25/PITX3 genes belong to an expanding family of bicoid-related vertebrate homeo box genes. These genes, like their Drosophila homologs, seem to play a role in the development of anterior structures and, in particular, the brain and facies."

REF

COD,LOC,EVO,EAG,MOU,HUM "Crawford MJ &: Mammal Genome, 8, 841-845, 1997
MOU,FUN,EVO "Lamonerie T &: Genes Dev, 10, 1284-1295, 1996
CLO,LOC "Shang J &: Genomics, 40, N1, 108-113, 1997

SWI

 SWISSPROT: P78337

KEY

trc, ont

CLA

coding, basic

LOC

05 q31

MIM

 MIM: 602149

SYN

PTX1 BFT