Gene: [05q32/HLADG] HLA-D, class II, gamma polypeptide (p33; invariant; antigen CD74); CD74 antigen (p33; invariant polypeptide of MHC class II antigen-associated); [DHLAG CD74 ]

COM

The GDB indicates regional location as 5q31-33.

GEN

The gene length: 12 kb.

PRO

Probe p7-2D-1446 (pBR322 derivative) contains a 1.44-kb cDNA fragment."

FAG

In contrast to other MHC complex genes (FAM:MHC/06p2133), which are members of immunoglobulin superfamily and are located in a small segment of chr 6p, HLADG gene shows no significant homology with IMM-superfamily members (FAM:IMM/00.0)."

REF

PRO,SEQ,EXP "Claesson &: PNAS, 80, 7395-7399, 1983
LOC,PRO "Claesson-Welsh &: Immunogenetics, 20, 89-93, 1985
LOC,PRO "Genuardi M, Saunders: Immunogenetics, 28, 53-56, 1988
GEN,PRO "Kudo J &: NAR, 13, 8827-8841, 1985
LOC,PRO "Lebo &: AJHG, 36, 101S, 1984
GEN,SEQ,EXP,EVO "O'Sullivan DM &: PNAS, 83, N12, 4484-4488, 1986

SWI

 SWISSPROT: P04233

KEY

imm

CLA

coding, basic

LOC

05 q32

MIM

 MIM: 142790

SYN

DHLAG CD74