Gene: [06p2133/HLADMB] major histocompatibility complex, class II, DM beta; [HLA-DMB ]

FUN

The HLA-DMB is required for the normal assembly of peptides with MHC class II molecules (FAM:MHC2/06p2133) and encodes subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation (see references in GEM:06p2133/HLADMA)."

REF

IDN,PRO,LIN,LOC,MAP "Kelly AP &: Nature, 353, 571-573, 1991
GEN,SEQ,EVO "Radley E &: JBC, 269, 18834-18838, 1994
GEN,MUT "Shaman J &: Immunogenetics, 41, 117-124, 1995

KEY

imm, img

CLA

coding, basic

LOC

06 p21.33

MIM

MIM: 142856

SYN

HLA-DMB