Gene: [06p2133/RNF3] ring finger protein 3; mitogen-activated nuclear kinase RING3; [RING3 ]

FUN

The RING3 product is a mitogen-activated nuclear kinase involved in signal transduction and is upregulated in certain types of leukemia (Denis-1996)."

FAG

Nomura-1994 revealed a second, non-MHC-linked copy of RING3 in humans (GEM:09q34/RING3L) and named it ORFX. Thorpe-1996 mapped ORFX to 9q34 by fluorescence in situ hybridization analysis."

REF

CLO,SEQ "Beck S &: DNA Seq, 2, 203-210, 1992
FUN "Denis GV, Green MR: Genes Dev, 10, N3, 261-271, 1996
CLO,SEQ "Nomura N &: DNA Res, 1, 223-229, 1994
IDN "Okamoto N &: Hum Immunol, 32, N3, 221-228, 1991
CLO,SEQ,STR,EVO "Thorpe KL &: Immunogenetics, 44, 391-396, 1996

KEY

sign, onc

CLA

coding, basic

LOC

06 p21.33

MIM

MIM: 601540

SYN

RING3

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