Gene: [06p213/NTRK4] neurotrophic tyrosine kinase, receptor, type 4; tyrosine kinase receptor E (trkE); cell adhesion kinase (CAK); protein tyrosine kinase CAK; discoidin domain receptor (DDR); neuroepithelial tyrosine kinase (NEP; MIM:600408); epithelial discoidin domain receptor 1 (EDDR1; MIM:600452);

COM

Edelhoff-1995, Sakuma-1996, Valent-1996 assigned the NTRK4 gene to Chr 6p21.3. Shelling-1995 mapped (likely the same) gene to Chr 6q16."

EXP

Long form CAK I and short form CAK II (differing by the absence of 37aa) are produced by alternative splicing."

REF

CLO,SEQ "Di Marco E &: JBC, 268, 24290-24295, 1993
CLO,LOC "Edelhoff S &: Genomics, 25, 309-311, 1995
CLO,SEQ "Johnson JD &: PNAS, 90, 5677-5681, 1993
CLO,SEQ "Laval S &: Cell Growth Differ, 5, 1173-1183, 1994
CLO,SEQ,STR,FUN "Perez JL &: Oncogene, 12, 1469-1477, 1996
LOC,SEQ "Perez JL &: Oncogene, 9, 211-219, 1994
CLO,SEQ "Playford MP &: Genome Res, 6, 620-627, 1996
CLO,SEQ,LOC "Sakuma S &: FEBS Lett, 398, N2-3, 165-169, 1996
CLO,SEQ,LOC "Shelling AN &: Genomics, 25, N2, 584-587, 1995
LOC "Valent A &: Hum Genet, 98, N1, 12-15, 1996

KEY

mem, onc, neu, recp, pep

CLA

coding, basic

LOC

06 p21.3

MIM

MIM: 601312

EZN

ENZYME: 2.7.1.112

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