Gene: [06p213/TUBB1] tubulin, beta-1 polypeptide; [M40 TUBB ]

FUN

 TUBB1 is a part of heterodimer, together with alpha-tubulin, representing the main structural component of microtubules. These in complex with micro- and intermediate filaments (e.g. neurofilaments) provide the spatial organization of cytoskeleton, intercellular transport, mitosis etc."

FAG

 See FAM:TUB/00.0.

REF

 REV,EVO "Barahona &: J Mol Biol, 202, 365-382, 1988
REV,EVO "Cleveland DW: Cell, 34, (Sep), 330-332, 1983
LOC,FAG "Floyd-Smith GA &: Exp Cell Res, 163, 539-548, 1986
PRO,SEQ,EXP,LOC,FAG,EVO "Lee MG &: Cell, 33, N2 (1 Jun), 477-487, 1983
PRO,SEQ,EXP,LOC,FAG "Lewis SA &: J Mol Biol, 182, 11-20, 1985
PRO,FAG,EVO "Sullivan KF, Cleveland DW: PNAS, 83, N12, 4327-4331, 1986
REV,EVO "Villasante A &: Mol Cell Biol, 6, N7, 2409-2419, 1986
PRO,SEQ,EXP,LOC,FAG "Wilde CD &: Nature, 297, (6 May), 83-84, 1982a
PRO,SEQ,EXP,LOC,FAG "Wilde CD &: Science, 217, (6 Aug), 549-552, 1982b

KEY

 cysk

CLA

 coding, basic

LOC

 06 p21.3

MIM

 MIM: 191130

SYN

 M40 TUBB

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