Gene: [06q2/PDNP1] alkaline phosphodiesterase I (EC:3.1.4.1); nucleotide pyrophosphatase 1 (EC:3.6.1.9); membrane component, chromosome 6, surface marker 1; plasma-cell membrane glycoprotein PC1 (homologous to mouse Ly-41 antigen);

FAG

Phosphodiesterase I (EC 3.1.4.1)/nucleotide pyrophosphatase (EC 3.6.1.9) enzymes are a family of type II transmembrane proteins that catalyze the cleavage of phosphodiester and phosphosulfate bonds of a variety of molecules, including deoxynucleotides, NAD, and nucleotide sugars. See GEM:08q241/PDNP2; GEM:06q22/PDNP3."

FUN

[1] EC:3.1.4.1. The reaction catalyzed: hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligo-nucleotides.
[2] EC:3.6.1.9. The reaction catalyzed: a dinucleotide + H(2)O = 2 mononucleotide."

SWI

 SWISSPROT: P22413

KEY

nucm, mem

CLA

coding, basic

LOC

06 q22-23

MIM

 MIM: 173335

EZN

 ENZYME: 3.1.4.1