Gene: [07p/RALA] simian leukemia viral oncogene homolog A (ras related); [RAL ]

FAG

[1] Ras-family includes H-, K-, N-, and R-RAS, as well as RHO and RAB genes located in different chromosomes (1,6,11,12,19,X).
[2] A ras-related protooncogene, RAL-B, has been mapped in chromosome 2 (GEM:02q1/RALB)."

LIN

Relatively close to RALA gene, loci for ERB-B1 oncogene (identical to the epidermal growth factor gene, EGRF) and T antigen receptor gamma subunit (FAM:TCR1G/07p15) are located; and very close to it a homeosis factor locus, HOXA (FAM:HOXA/07p1), is located."

EVO

The protein RAL-A is 50% homologous to P21-RAS protein, which is biochemically similar to G proteins participating in the signal transmission in various receptor-effector systems."

PRO

Probe PGEM3 contains a 0.6-kb cDNA fragment (5' region) cloned at EcoRI site."

REL

FAM:GNBP/00.0

REF

PRO "Chardin, Tavitian: EMBO J, 5, 2203-2208, 1986
LOC,FAG "Rousseau-Merck MF &: Hum Genet, 79, 132-136, 1988

SWI

 SWISSPROT: P11233

KEY

onc

CLA

coding, basic

LOC

07 p21.2-15.3

MIM

 MIM: 179550

SYN

RAL