Gene: [07q/ASNS] asparagine synthetase (glutamine-hydrolyzing); cell cycle control protein TS-11 (temperature sensitivity complementing);

COM

There are two ASNS-like sequences assigned to different cromosomes (GEM:08^/ASNSL1; GEM:21^/ASNSL2)."

FUN

Systematic name: L-aspartate:L-glutamine amidoligase (AMP-forming). Reaction catalyzed: ATP + L-aspartate + L-glutamine = = AMP + pyrophosphate + L-asparagine + L-glutamate."

REL

GEM:08^/ASNSL1; GEM:21^/ASNSL2; GEM:07^/GCF1; GEM:08^/ASNSL1; GEM:08q2/BN51T; GEM:08p21/BN51TL1; GEM:0Xq131/TAF2A; GEM:10q211/CDC2; GEM:17p131/TP53."

REF

CLO,COD,SEQ,EXP "Andrulis IL &: Mol Cell Biol, 7, 2435-2443, 1987
LOC,CYG "Arfin SM &: Somat Cell Genet, 9, N5, 517-531, 1983
LOC,CYG,MOL,FAG "Greco A &: Genomics, 4, 240-245, 1989
CLO,COD,SEQ,EXP "Greco A &: PNAS, 84, N6, 1565-1569, 1987
LOC,MOL,PRO "Lambert MA &: AJHG, 39, A207, 1986
CLO,COD,SEQ,EXP "Van Heeke G, Schuster M: JBC, 264, N10, 5503-5509, 1989
CLO,GEN,SEQ,STR "Zhang YP &: Genomics, 4, 259-265, 1989

SWI

SWISSPROT: P08243

KEY

aac, repr

CLA

coding, basic

LOC

07 q21-31

MIM

MIM: 108370

EZN

ENZYME: 6.3.5.4