Gene: [08p1/ADRB3] adrenergic, beta-3-, receptor;
FUN | The beta-3-adrenergic receptor, located mainly in adipose tissue, is involved in the regulation of lipolysis and thermogenesis." |
ASS | The potential relevance of ADRB3 to obesity in humans, proposed by Clement et al. (Clement-1995), was not confirmed in several studies (Elbein-1996, Gagnon-1996, Elbein-1996, Nagase-1996)." |
FAG | See GEM:20^/ADRA1A. |
REF | ASS,FUN,MUT "Clement K
&: New Engl J Med, 333, 352-354, 1995 ASS,POP,MUT "Elbein SC &: J Clin Endocrinol Metab, 81, 4422-4427, 1996 ASS,POP "Gagnon J &: J Clin Invest, 98, 2086-2093, 1996 ASS,POP,FOG,MUT "Nagase T &: J Clin Endocrinol Metab, 82, 1284-1287, 1997 GEN,SEQ,EVO "Van Spronsen A &: Eur J Biochem, 213, 1117-1124, 1993 LOC,LIN "Wilkie TM &: Genomics, 18, 175-184, 1993 |
SWI | SWISSPROT: P13945 |
KEY | neu, recp, mem, sign |
CLA | coding, basic |
LOC | 08 p12-11.1 |
MIM | MIM: 109691 |
