Gene: [08p/CYRN1] cyritestin 1; [ADAM3 ]

COM

By isotopic in situ hybridization, the CYRN1 gene was mapped to Chr 8p21-12 (Adham-1998)."

FUN

Cyritestin is a cysteine-rich transmembrane protein located in testis, hence its name. Germ cell cyritestin, like other members of the ADAM family of proteins, may be important for sperm-egg fusion during fertilization."

FAG

Another gene coding for cyritestin 2 is mapped: GEM:16q121/CYRN2.

REF

CLO,LOC,EXP,FAG "Adham IM &: DNA Cell Biol, 17, 161-168, 1998
PRO,FAG "Koehler MR &: CCG, 77, 178-179, 1997
MOU,EAG "Lemaire L &: Genomics, 21, 409-414, 1994

KEY

mem

CLA

coding, basic

LOC

08 p21-12

MIM

MIM: 602889

SYN

ADAM3