Gene: [09p/ACO1] aconitase 1, soluble (aconitate hydratase C, cytosolic);
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COM |
The GDB and HGM catalogues indicate a wider region for the ACO1 localization, p22-q32. The MIM and GEM-catalogues indicates as the regional location the smallest region of overlapping (SRO), 09p22-13." |
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FUN |
Systematic name: citrate(isocitrate) hydro-lyase. Reaction catalyzed: citrate = cis-aconitate + H(2)O; /note: cis-aconitate is used to designate the isomer (z)-prop-1-ene-1,2,3-tricarboxylate. Also converts isocitrate into cis-aconitate." |
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FAG |
A gene for the mitochondrial form of aconitase is mapped to chr 22: GEM:22q1/ACO2." |
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REL |
GEM:09^/IREB1 |
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REF |
LOC,CYG,FAG "Carritt B &: CCG, 25, (HGM5), 140, 1979 LOC,LIN "Cook PJ &: Ann Hum Genet, 41, 365-377, 1978 LOC "Mattei MG &: CCG, 37, (HGM7), 533, 1984 LOC,CYG,FAG "Mohandas T &: AJHG, 31, 586-600, 1979 LIN,LOC,EVO "Nadeau, Eicher: CCG, 34, 271-281, 1982 LOC,CYG,FAG "Povey S &: Ann Hum Genet, 39, 413-422, 1976 LOC,CYG,FAG "Shows TB, Brown: CCG, 19, 26-37, 1977 |
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KEY |
cytr |
|
CLA |
coding, basic |
|
LOC |
09 p22-13 |
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MIM |
MIM: 100880 |
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EZN |
ENZYME: 4.2.1.3 |
