Gene: [09q/FPGS] folylpolyglutamate synthetase (GAT-minus auxotroph);

FUN

Systematic name: tetrahydrofolate:L-glutamate gamma-ligase (ADP forming). Catalyzes reaction: ATP + tetrahydrofolyl-[Glu](n) + L-glutamate = = ADP + orthophosphate + tetrahydrofolyl-[Glu](n+1)."

REF

LOC,CYG,LIN "Florian &: CCG, 51, (HGM10), 999, 1989
LOC,CYG,LIN "Jones C, Kao: CCG, 37, (HGM7), 499-500, 1984
LOC,CYG,LIN "Jones C &: CCG, 28, N3, 181-194, 1980
HIS "Kao, Puck: PNAS, 60, 1275-1281, 1968
EXP "Sussman &: Somat Cell Mol Genet, 12, 531-540, 1986
HIS "Taylor, Hanna: Arch Biochem Biophys, 181, 331-344, 1977

SWI

SWISSPROT: Q05932

KEY

aac

CLA

coding, basic

LOC

09 c-q34

MIM

MIM: 136510

EZN

ENZYME: 6.3.2.17

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