Gene: [09q/FPGS] folylpolyglutamate synthetase (GAT-minus auxotroph);
FUN | Systematic name: tetrahydrofolate:L-glutamate gamma-ligase (ADP forming). Catalyzes reaction: ATP + tetrahydrofolyl-[Glu](n) + L-glutamate = = ADP + orthophosphate + tetrahydrofolyl-[Glu](n+1)." |
REF | LOC,CYG,LIN "Florian
&: CCG, 51, (HGM10), 999, 1989 LOC,CYG,LIN "Jones C, Kao: CCG, 37, (HGM7), 499-500, 1984 LOC,CYG,LIN "Jones C &: CCG, 28, N3, 181-194, 1980 HIS "Kao, Puck: PNAS, 60, 1275-1281, 1968 EXP "Sussman &: Somat Cell Mol Genet, 12, 531-540, 1986 HIS "Taylor, Hanna: Arch Biochem Biophys, 181, 331-344, 1977 |
SWI | SWISSPROT: Q05932 |
KEY | aac |
CLA | coding, basic |
LOC | 09 c-q34 |
MIM | MIM: 136510 |
EZN | ENZYME: 6.3.2.17 |