Gene: [0Xp2232/ARSC1] arylsulfatase C, S isozyme (slow form); steroid sulfatase, microsomal; ichthyosis X-linked (steroid sulfatase deficiency);

FAG

[1] On Y-linked homolog of ARSC1 (or STS) see GEM:0Yq11/ARSC1P.
[2] About isozyme F of arylsulfatase C see GEM:0X^/ARSC2."

FUN

Systematic name: steryl-sulfate sulfohydrolase. Catalyzes reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H(2)O = = 3-beta-hydroxyandrost-5-en-17-one + sulfate."

REF

LOC,LIN,MAP "Ballabio A &: CCG, 51, (HGM10), 957, 1989
PRO,LOC "Ballabio A &: PNAS, 84, N13, 4519-4523, 1987
MUT "Basler E &: AJHG, 50, 483-491, 1992
MUT "Bernatowicz LF &: Genomics, 13, 892-893, 1992
PRO,MUT "Bonifas JM &: PNAS, 84, N24, 9248-9251, 1987
LOC,LIN,FAG "Chang &: AJHG, 46, 729-737, 1990
PRO,MUT "Conary JT &: BBRC, 144, 1010-1017, 1987
PRO,LOC "Gillard EF &: NAR, 15, 3977-3985, 1987
PHE,PND "Hardardottir &: Clin Genet, 35, N3, 224, 1989
MAP "Mondelo &: Ann Hum Genet, 51, 137-143, 1987
ASS,HET "Robledo R &: Am J Med Genet, 59, 143-148, 1995
MAP "Yates JR &: Genomics, 1, 52-59, 1987
SEQ,EXP,MUT "Yen PH &: Cell, 49, 443-454, 1987

SWI

SWISSPROT: P08842

KEY

lip, ster, derm, horm

CLA

coding, basic

LOC

0X p22.32

MIM

MIM: 308100

EZN

ENZYME: 3.1.6.2

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