Gene: [10q2/VCL] vinculin (alpha-actinin and talin binding protein);

GEN

The cDNA is 5.1 kb in size and consists of three domains: the 5'-UTL region (44 bp), the complete coding region (3198 bp = 1066 amino acids), and 3'-UTL region (1852 bp). For the deduced amino acid sequence, MM = 116.7 kD."

REF

FUN,MEB "Belkin, Koteliansky: FEBS Lett, 220, 291-294, 1987
FUN,MEB "Blanchard &: J Muscle Res & Cell Motil, 10, 280-289, 1989
FUN,MEB "Burridge, Mangeat: Nature, 308, 744-746, 1984
FUN,MEB "Wachsstock &: BBRC, 116, 1026-1032, 1987
CLO,COD,SEQ,EXP,EVO,HUM,VER,LOC "Weller PA &: PNAS, 87, N15, 5667-5671, 1990

KEY

mem, exce, cysk

CLA

coding, basic

LOC

10 q22-23

MIM

MIM: 193065

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