Gene: [11p15/NELL1] nel (chicken)-like 1;
|
COM |
By using fluorescence in situ hybridization the NELL1 gene was mapped to human chromosome 11p15.2-p15.1 (Watanabe-1996)." |
|
MOP |
The NELL1 open reading frame encodes an 810-amino acid polypeptide. The NELL1 amino acid sequence includes a secretory signal sequence but no transmembrane domains and exhibits 50% identity to that of chicken 'nel.' The NELL1 was expressed weakly as a 3.5-kb transcript in human adult and fetal brain and kidney tissues (Watanabe-1996)." |
|
FAG |
Two NELL genes whose sequences contained 6 EGF-like repeats and resembled the chicken gene 'nel' have been found (Watanabe-1996). On nel-like 2 gene see in GEM:12q131/NELL2." |
|
REF |
COD,SEQ,LOC,FAG "Watanabe TK &: Genomics, 38, 273-276, 1996 |
|
KEY |
ont |
|
CLA |
coding, basic |
|
LOC |
11 p15.2-.1 |
|
MIM |
MIM: 602319 |
