Gene: [11q22/CASP4] caspase 4, apoptosis-related cysteine protease (TX protease); interleukin 1, beta convertase (Ice/Ced-3) homolog 2;
FUN | Acts as a negative regulator of programmed cell death. |
REF | CLO,SEQ "Faucheu C &:
EMBO J, 14, 1914-1922, 1995 CLO,SEQ,LOC "Kamens J &: JBC, 270, 15250-15256, 1995 CLO,SEQ "Munday NA &: JBC, 270, 15870-15876, 1995 LOC "Nasir J &: Mammal Genome, 8, N8, 611-613, 1997 |
SWI | SWISSPROT: P49662 |
KEY | pep, imm, ont |
CLA | coding, basic |
LOC | 11 q22.2-.3 |
MIM | MIM: 602664 |
EZN | ENZYME: 3.4.22.? |
Ссылки:
- Gene: [11q22/CASP1] caspase 1, apoptosis-related cysteine protease; interleukin 1, beta, convertase;
- Gene: [07q35/CASP2] caspase 2 (NEDD2 apoptosis regulatory gene); protease ICH-1 (isoforms L and S); neural precursor cell expressed, developmentally down-regulated 2; holoprosencephaly?;
- Гены ced-3 и ced-4: Роль в апоптозе